Table 1

20th century vs. 21st century biomedical science

20th Century

21st Century

discipline centered

problem centered

hypothesis testing

hypothesis searching

collect only the data needed to test an hypothesis

collect extra data needed for the future

data archiving

data mining (discovery in databases)

individual scientists and their fiefdoms

flexible, collaborative, multidisciplinary teams

Smalheiser Journal of Biomedical Discovery and Collaboration 2006 1:1   doi:10.1186/1747-5333-1-1